Our mission is to improve the medical treatment of Lower Urinary Tract Symptoms (LUTS) in aging men that are linked to benign prostate disease. LUTS represent a cluster of urinary problems that affects the aging male population worldwide significantly deteriorating their quality of life. Our limited knowledge on the disease pathology prevents us from developing more efficacious therapies. Our goal is to identify the molecular mechanism of inflammation-induced pathological changes in the prostate through translational research and the development of animal and cellular models.